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Animals also presented a reduction of tight junction protein ZO-1, suggesting other effects into BBB, and exhibited augment in lipid peroxidation in the brain [29]

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This orientation allows it to interact with ROS on both sides, helping stabilize and protect the cell.19 Laboratory studies show that this structural advantage may make astaxanthin 10100 times more potent than vitamin E or beta-carotene in quenching singlet oxygen, one of the most reactive and damaging forms of oxygen in the body.20 40 Because of this positioning, astaxanthin can influence how cells respond to stress, potentially protecting lipids, proteins, and DNA from oxidation.39 In human studies, its effects appear to stem mainly from two biological roles: reducing oxidative and inflammatory stress and supporting mitochondrial health the processes that govern cellular energy and resilience.21 41 These mechanisms appear to underlie many of the outcomes observed in clinical research

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