Cell 179 , 14691482.e11 (2019)
Originally developed to treat Type 2 diabetes, they turned out to have a powerful side effect: significant weight loss
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The compound is one of the most-studied peptides in preclinical regenerative-research literature, with more than 100 published animal studies covering gastric and intestinal cytoprotection, tendon and ligament repair, angiogenic pathway activity, and central nervous system models
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Drug development studies have utilized Angptl4 to determine whether small molecule LPL activators can enhance LPL activity and reverse Angptl4-mediated inhibition (72)