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Condensation approach to aliphatic oligourea foldamers: helices with N-(pyrrolidin-2-ylmethyl)ureido junctions

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Patients taking both require closer monitoring during Wegovy dose titration, including cardiovascular parameter checks (heart rate and blood pressure) and caloric intake tracking to ensure adequate nutrition

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By using 1-tert-butyl-3-ethylcarbodiimide (TBEC) as a safer coupling reagent in combination with eco-friendly solvent systems like dimethyl sulfoxide (DMSO) and butyl acetate (BuOAc), we reduced the environmental footprint and safety risks commonly associated with traditional synthesis methods