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DS-8500a, an orally available G protein-coupled receptor 119 agonist, upregulates glucagon-like peptide-1 and enhances glucose-dependent insulin secretion and improves glucose homeostasis in type 2 diabetic rats

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This benefit is particularly valuable for individuals with prediabetes, metabolic syndrome, or type 2 diabetes

Fukui, The Science and Technology of Carbon Nanotubes , 1st edn

Discussion We have conducted the largest real-world retrospective cohort study to date investigating the safety and outcomes of individuals with type 1 diabetes using SGLT2i and GLP-1 RA therapy, and the first to report cardio-renal benefits

GLP-1 medications work on brain reward pathways and appetite centres, potentially reducing food cravings and loss-of-control eating beyond simple hunger suppression