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HA integrity has also been shown to critically modulate TGF--driven fibroblast differentiation, as enzymatic fragmentation suppresses -smooth muscle actin (-SMA) and collagen type I expression, emphasizing the importance of balanced HA turnover for proper ECM remodeling and scar resolution [9]

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This is the model Ilant is built on, matching each member to the right treatment instead of averaging care across an entire population

In addition, we are grateful to Holly Clifford for her excellence in project management for this research program