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These mediators contribute to central appetite control and neuronal plasticity, while FGF21, especially stimulated by resistance exercise, further modulates hypothalamic circuits and promotes the browning of white adipose tissue, enhancing thermogenesis (45)

Unlike conventional medications that target a single pathway, tirzepatide uniquely acts on both GLP-1 and GIP receptors

Due to potential side effects and legal considerations, thorough research and professional consultation are crucial before use.

They're both effective tools and the best approach depends on the individual, but it doesn't have to be either or

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