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Regarding environmental factors, high iodine intake, selenium deficiency, pollutants such as tobacco smoke, infectious diseases such as chronic hepatitis C, and certain drugs are implicated in the development of autoimmune thyroiditis (16.1: Duntas LH

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Preliminary data on cows reared in polluted areas show increased expression of e-GST, which parallels the results found for humans

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So split a half dose in the morning and a half at night