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In honor of patient#1, the investigators named this novel ACOX1-mediated disease Mitchell Syndrome (distinct from Mitchell's disease, Erythromelalgia)

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Visomitin exhibited excellent renal protective effects in FA-, cisplatin-, and IR-induced models by reducing lipid peroxidation and mitochondrial ROS generation to ameliorate ferroptosis in kidneys in vivo and in vitro [189]

J.van der VeerE.et al (2020)

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Medved I, Brown MJ, Bjorksten AR: N-acetylcysteine enhances muscle cysteine and glutathione availability and attenuates fatigue during prolonged exercise in endurance-trained individuals