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AHK-Cu has been studied in this context for its possible contribution to enhancing VEGF signaling, which may in turn support fibroblast and endothelial cell activity

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Together with the absence of symptoms associated with IGF-1-mediated effects such as fluid retention, tissue edema, or impaired glucose tolerance, these results demonstrate that AOD-9604 does not activate the growth hormone/IGF-1 pathway and therefore functions through an entirely appetite-independent mechanism

Pale or jaundiced skin A shortage of healthy red blood cells can make skin look pale or slightly yellow