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Transient cell cycle arrest and arterial differentiation of vein-derived Esm1 + cells Consistent with this and previous studies, the venous EC subclusters in our scRNA-seq analysis predominantly harbor proliferative cells in the G2/M or S phase (Fig

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Malhotra A et al., SURMOUNT-OSA, NEJM 2024 (NEJMoa2404881, PMID 38912654) : tirzepatide and obstructive sleep apnea, AHI -25,3 to 52 weeks