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We previously identified cytosolic acidification as another phenotype specific to CYS4 -OE ( CYS4-OE , YAK1-OE induced cytosolic acidification and that combined effect of CYS4-OE and YAK1 -OE on cytosolic pH was additive (Figure 1E)
The most common signs include difficulty falling asleep, frequent waking, restless nights, shallow sleep, and waking up tired even after a full night in bed
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Data last updated 07/07/2026
This suggests that the mechanism of radiosensitization may involve the regulation of innate immunity through defective Gln metabolism (93)
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