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In psoriasis, SCFAs exert their effects through: (i) activation of GPCRs and inhibition of HDACs, (ii) regulation of both innate (neutrophils, macrophages, dendritic cells) and adaptive (T and B lymphocytes) immune responses, particularly correcting Th17/Treg imbalance, and (iii) maintenance of gut barrier integrity [138]

S., Wang, Z., Abdel-Mohsen, M., Chen, X

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In specific research, mouse models were subjected to exposure with either Ipamorelin or a control