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One of them (also labeled as treatment failure) demonstrated good efficacy, yet amitriptyline was discontinued because of narcolepsy, and episodes returned

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Furthermore, knockdown of GPX4 did not enhance the ERS signal induced by H 2 O 2 , but the lack of GPX4 would cause further deterioration of ER stress signal in the absence of SELS

References 1 Khavinson V.Kh