The standard initial loading dose is 1,000 mcg administered intramuscularly (IM) once weekly for 4 weeks
Growing evidence identifies mitochondrial dysfunction, including abnormalities in mitochondrial DNA, impaired bioenergetics, disrupted quality control, and redox imbalance, as a central pathological feature of MDD
Data availability The datasets used and/or analyzed during the current study available from the corresponding author on reasonable request
It also protects the solution from potential temperature spikes in the lab or storage room
In contrast, inhibition of autophagy by intravitreal injection of 3-methyladenine, a potent inhibitor of autophagosome maturation, was neuroprotective in ischemia and chronic IOP elevation rat models 22,23
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