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FOXO3 also prevents pro-apoptotic BAX translocation to the mitochondria, hence protecting cells from apoptosis 100

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Cagrilintides mechanism provides additive or synergistic potential when studied alongside incretin-based therapies

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v) regardless of the presence or absence of dyslipidemia, the oxidative stress status, highlighted by the decrease of GPx, triggers lipid oxidation, with the formation of anti-LDL-oxidized antibodies, leading to the onset of vascular endothelial aggression, with early atherogenic pathology