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Since fibrosis is the most compelling predictor of outcomes, current and future therapies must focus on improving fibrosis by indirectly reducing pro-fibrotic inflammatory signaling or directly abrogating fibrosis

Expected availability includes LillyDirect starting April 6 and later through retail pharmacies

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In 2023, semaglutide (the active ingredient in Wegovy & Ozempic) was added to updated PCOS treatment guidance due to its ability to address insulin resistance

According to previous studies, liraglutide attenuates myocardial hypertrophy and fibrosis following angiotensin II infusion by suppressing TGF-1/Smads signaling pathways [49]

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