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J Immunol 168(3):14051412

These findings indicate that MC3R activity may play an important role in producing tolerable and clinically meaningful weight loss in a more diverse patient population

This could potentially lead to unwanted weight gain in some individuals

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Side effects in long term trials Side effects in long term trials Though GLP-1 receptor agonist drugs like Wegovy and Ozempic may seem new to the public, these drugs have been tested in patients for decades

Key Advances in AMY3R/CTR-Targeted Drug Discovery To facilitate drug discovery targeting amylin/calcitonin receptors, the ICE team evaluated non-lipidated peptide hCT and human amylin and the lipidated peptide cagrilintide using the HTRF-cAMP assay across multiple host cell lines