2.3 Cell culture and treatment The human normal hepatic cell line LO2 (Shanghai Institute of Biological Sciences, Chinese Academy of Science, Shanghai, China) was maintained in DMEM(BI,United States) containing 10% FBS (Gibco, United States) and 1% penicillin/streptomycin (Gibco, United States) in a 5% CO2 humidified 37C incubator
In this work, we investigate the molecular mechanisms by which GLP-1, oxyntomodulin, exendin-4, and exendin-P5 bind and activate the GLP-1R using a combination of structural biology, molecular dynamics simulations, and pharmacological studies combined with extensive receptor mutagenesis
These medications are also known as GLP-1 analogs, incretin mimetics, and GLP-1 RAs
Can I add other peptides to this stack
It does not provide medical advice or instructions for human use
10.3390/molecules24020321 281 WangL.O'MaraM