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Patients with a history of depression have significantly increased levels of amyloid plaques and neurofibrillary tangles in the brain, and those with depression and amyloid deposition are more likely to develop dementia [100]

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RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis

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Additionally, certain cellular events including autophagy, endoplasmic reticulum stress, inflammatory infiltration and microcirculatory dysfunction, have been found involvement with the pathogenesis of APAP-caused liver injury (Yan et al., 2018)

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