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However, the complexity of balancing three different receptor pathways creates new challenges for dose optimization and safety management

Troshin PV, et al

Moreover, the analysis has not yet thoroughly investigated gender differences or age-based variations in weight regain, which could open avenues for future research

In addition, we observe that rotation of TM6 in the active-state structure breaks the interaction between S247 6.44 and NPxxY motif residue N296 7.49 , allowing local rearrangement of NPxxY motif residues P297 7.50 and Y300 7.53

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