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Compounded versions of GLP-1 medications have not been the subject of long term studies, and may have different results

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Updated 2026-05-25

In contrast to most prior obesity treatment trials that focused on caloriereduced diets as the background lifestyle intervention, the recommendations in the TRIUMPH program align with recent guidance on the role of healthy lifestyle interventions in the setting of highly effective obesity management medications

No major safety red flags caused trial termination, which was encouraging, but the presence of independent oversight adds credibility to the findings and demonstrates the cautious approach taken with each dose

Nersessian RS, da Silva LM, Carvalho MA, Silveira SQ, Abib AC, Bellicieri FN, et al