[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Perovic D., Milavic M., Dokuzovic S., Krezic I., Gojkovic S., Vranes H., Bebek I., Bilic V., Somun N., Brizic I., et al
This broad spectrum of activity makes GHK-Cu a molecule of significant interest in preclinical studies related to dermatology, regenerative medicine, and cellular senescence
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With a molecular weight of just 403.93 Da well below the 500 Da cutoff typically associated with significant skin penetration GHK-Cu is small enough to penetrate the stratum corneum (outer skin layer) in concentrations sufficient to activate regenerative processes
[7] [8] It turned out that this effect was due to a small peptide factor that behaved similarly to the synthetic peptide glycyl-L-histidyl-L-lysine (GHK)