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specifically, Nonarteritic Anterior Ischemic Optic Neuropathy (NAION), a rare condition causing sudden and possibly permanent vision loss

After a 2-week placebo run-in period, patients who had a seated systolic blood pressure of 135 mm Hg or more were assigned to receive baxdrostat (1 mg or 2 mg) or placebo once daily for 12 weeks

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doi: 10.2147/dddt.S222127 130 BostanceriNTalidereAElbeHTaldereE

For perimeter duration ( Figure 5B ), we also found no significant effects of Access Duration (F(1,28)=1.652

This evidence gap highlights a critical disconnect between compelling biological mechanisms and the level of proof required for widespread clinical implementation