These new findings encourage a novel working hypothesis for further research, that a chemical-modification mechanism enables transformation of HGF through interaction or reaction with LASSS under physiological conditions, resulting in the retention of HGFs biological activity after exposure to peroxynitrite, at least until an enhanced form of HGF undergoes metabolic turnover in vivo
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Among the ROS, OH is the most potent damaging radical, and can react with all biological macromolecules (lipids, proteins, nucleic acids and carbohydrates)
Massage thoroughly for 1-2 minutes to distribute product and stimulate absorption
Free copper ions generate reactive oxygen species through Fenton-like reactions
Rather than acting as a stimulant alone, GHK-Cu appears to function as a tissue-remodeling and repair signaling peptide