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Diabetic nephropathy Patients with poorly controlled type 1 diabetes mellitus (T1DM) present with markedly enhanced pituitary GH-secretion rates, probably related to decreased hypothalamic somatostatin tone and exaggerated GH-responses to physiological and pharmacological stimuli [186, 187]

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Kuczewski N, Porcher C, Ferrand N, Fiorentino H, Pellegrino C, Kolarow R, Lessmann V, Medina I, Gaiarsa JL

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Fruitful developments have also occurred by accident