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There have been postmarketing reports of acute pancreatitis, though causality remains uncertain

doi: 10.5314/wjd.v9.i1.1 534 BrodmannTEndoAGueimondeMVinderolaGKneifelWde VosWMet al

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This effect appears to correlate with downregulation of genes encoding antigen processing components and 2M rather than downregulation of Class I genes themselves