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A patient with established coronary artery disease taking semaglutide for secondary prevention has even more reason to avoid NSAIDs, which have their own cardiovascular risk profile including increased myocardial infarction risk with chronic use

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The mechanisms behind this relationship are multifactorial

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Additionally, Semaglutides ability to lower blood glucose levels benefits NAFLD patients with type 2 diabetes, reducing the risk of liver-related complications