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The FDA clinical studies were focused around correction of moderate to severe facial wrinkles and folds, such as nasolabial folds in adults over the age of 21

The commenter explained that the low utilization for both codes caused a lack of reliable claims data for ratesetting and urged us to assign the codes to a clinical APC with a higher payment rate to ensure patient access

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Naturally present in plasma, saliva, and urine, its levels decline with age, correlating with slower healing and visible tissue degeneration