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[1] [2] The liver is involved in the metabolism of the peptide structure, but significant hepatic impairment does not dramatically alter elimination times

Pharmacol Res 216: 107770

If heartburn or nausea is a problem, avoid fried foods and spicy foods, and dont lie down after meals

Others are more conservative due to concerns about the high costs, access issues, side effects, and lack of longitudinal data on long-term outcomes