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In the mitochondrial sulfide oxidation pathway, SQOR, a flavin adenine dinucleotide (FAD)-dependent enzyme, initiates H 2 S oxidation coupled with the reduction of coenzyme Q (CoQ or ubiquinone) (Landry et al., 2021)

This is especially concerning for humans, as the molecular signalling in human disease is far more complex than in many animal models ( Figure 2 schematizes the two faces of lipid peroxidation