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PRPP is an intermediate in purine nucleotide synthesis, generated from ribose 5-phosphate from the pentose phosphate pathway 21

During one experiment using a murine model, Pal-GHK was suggested to suppress the activation of Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-B) and p38 mitogen-activated protein kinase (MAPK) signaling pathways, both of which are associated with inflammation

Altern Med Rev 1997;1:155-176

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doi:10.1111/acel.12368 Lu J, Wang Z, Cao J, Chen Y, Dong Y