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When patients hear that TB-500 may help recovery, they should ask a more precise question: what evidence exists for this exact compound, for this exact condition, in humans, using a medically appropriate formulation and treatment plan

For most healthy adults, 1,000mg of vitamin C daily is considered safe and is well below the upper tolerable intake level of 2,000mg

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Therefore, it is possible that the increased mTORC1 activation measured in FoB upon Gclc deletion can be a consequence of ROS accumulation and activation of the PI3K/AKT axis