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In addition to enzymes, liver-derived metabolites such as branched-chain amino acids (BCAAs) and ammonia are critically involved in AD-related cognitive dysfunction

Combined with the above research results, we can use these substances regulating oxidative stress as potential therapeutic drugs for KOA and verify the ability of these substances to regulate ROS in the pathogenesis of KOA in animal experiments

PMID: 4097650

The normality of data distribution was assessed using Shapiro-Wilks test

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According to the National Institutes of Health, It transports long-chain fatty acids into the mitochondria so they can be oxidized (burned) to produce energy, all while preventing toxicities from building up