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In dogs at 52 weeks of treatment at the NOAEL of 40 mg/kg, which is approximately 3 times the MRHD (400 mg) on a mg/m2 body surface area, the AUC7d values were approximately 59 mcgh/mL in males and 44 mcgh/mL in females

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Mass spectrometry analyses were carried out by Trong Khoa Pham at the biOMICS/chemMS Facility of the Faculty of Science Mass Spectrometry Center at the University of Sheffield, by William S

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In rodents and humans, Delta sleep-inducing peptide (DSIP) influence in the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH) and growth hormone (GH)