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Dhiman P, Rajora N, Bhardwaj S, Sudhakaran SS, Kumar A, Raturi G et al (2021) Fascinating role of silicon to combat salinity stress in plants: An updated overview

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Berberine side effects are predominantly gastrointestinal and may include: Diarrhoea, constipation, or abdominal discomfort Nausea and flatulence Cramping or bloating These effects are typically dose-dependent and may be minimised by starting with lower doses and taking berberine with meals