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Exendin-4 treatment reversed the intracerebroventricular-streptozotocin (ICV-STZ) -induced decline in the levels of phosphorylation of Akt at Ser473 and glycogen synthase kinase 3 (GSK-3) at Ser9, a key kinase in AD, leading to decrease hyperphosphorylation of tau in rat hippocampus (182)

GIP promotes the proper storage of lipids in adipose tissue, whereas the robust fat oxidation mechanism of GLP-1 increases the utilization of these deposited lipids

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