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Some anecdotal reports and preliminary long-term studies suggest that continuous treatment could help preserve positive behavioral changes, but definitive evidence is lacking

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Relevant model outputs include life expectancy, quality-adjusted life expectancy (expressed in quality-adjusted life years [QALYs]), direct costs, time to onset of diabetes-related complications, cost-effectiveness scatterplots and acceptability curves, and incremental cost-effectiveness ratios (ICERs)

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This unique mechanism potentially offers enhanced benefits for weight management and glycemic control

Patients with simple steatosis who have not yet progressed to MASH lack approved pharmacological options, and current clinical management primarily depends on lifestyle modification, which is often limited by poor adherence and inconsistent therapeutic outcomes