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PMC 5114298

Specifically, GLP-1RAs exert protective effects on exercise-induced cardiomyopathy via increasing autophagy, reducing inflammation-related proteins and ROS generation via restoring the expression of catalase and manganese superoxide dismutase (MnSOD) [81]

With reduced appetite, hitting this target requires strategy

Measuring body composition (fat versus lean mass) should become routine in the management of patients on GLP-1 medications. The Takeaway While GLP-1 medications are effective for weight loss, rapid weight reduction can lead to significant loss of fat-free mass, including muscle

Drugs that raise blood glucose (such as corticosteroids, certain antipsychotics, or thiazide diuretics) may counteract glycaemic benefits

Despite widespread claims on social media and unregulated websites, no GLP-1 patches are currently approved or available for clinical use in the UK