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While preclinical studies suggest neuroprotective benefits, long-term clinical data in humans are limited, and further research is needed to determine whether these effects occur via the gut-brain axis or direct antioxidant activity

Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle

J Magn Magn Mater 468:148154

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26 With several toxic metals lacking robust pathways for elimination or otherwise remaining in the body for along time, body burdens of some toxic metals (eg, lead, mercury, cadmium) may increase with age

10.1016/j.neurobiolaging.2016.08.019 69 CekanaviciuteE.YooB