Its administration after spinal cord injuries has been associated with improved neuronal recovery and better motor function, highlighting its potential as a therapeutic agent in neurorehabilitation
\n\n\n\n It is critical to note, however, that preclinical safety data no matter how consistently positive cannot be directly extrapolated to humans without proper clinical trials
The dose escalation design tested different starting doses (2 mg vs 4 mg) to evaluate tolerability
This makes overdose extremely rare , but that doesnt mean more is always better
Specifically, STS injected intra-arterially may not have enough time to react with endothelium, being both absorbed and inactivated by formed elements in the blood and serum factors and thereby being diluted to a safe concentration by the more rapid arterial flow
Q: What if the powder does not dissolve fully