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Ferroptosis does not require a specific pro-death signaling pathway but is triggered spontaneously when the protection of cellular membrane phospholipids from peroxidation by the metabolites and enzymes, including cysteine and glutathione peroxidase 4 (GPX4), are weakened [228, 229]

(2024) 39:e259

Research has shown that oxidative stress can lead to increased bone resorption, the process by which bone is broken down, thereby weakening the skeletal structure

S., Santos, G

Studies report that preservatives like sodium benzoate and sodium metabisulfite reduce glutathione levels in the body

Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression