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Some people are better candidates than others for medically supported weight loss, especially if a GLP-1 prescription is involved

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Insulin resistance itself is a major cardiovascular risk factor independent of lipid levels

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GLP-1 medication alone was associated with bone density decline at the hip and spine

This vertically integrated interpretation avoids separating molecular pathways from their cellular consequences and highlights cavernous fibrosis and contractile imbalance as key pathological outcomes