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The study design was two randomized, placebo-controlled, double-blind, ascending dose trials with durations of 28 and 49 days

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Interestingly, a 0.25 protective effect with a 0.95% CI of 0.160.39 was observed in patients undergoing EGD combined with colonoscopy [16]

Cancer Cell (2017) 32(1):4256.e6

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