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Chemoproteomic studies using the active isomer of RSL3 as an affinity reagent identified the selenoprotein glutathione peroxidase 4 (GPX4, PHGPx) as a candidate target of this compound [6] (Fig

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A: It supplies glutathione directly or provides amino acids used to produce it

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Therefore, it can be postulated that treatment of human chronic wounds with glutathione both systemically and locally after debridement can be effective in resolving chronicity.[] ANTIVIRAL ROLE Although yet not fully elucidated, the role of glutathione as an antiviral has been studied