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However, GLP-1 medication does not replace the need for behavior change

Some clinicians recommend reducing to the lowest effective dose for several weeks while intensifying behavioral interventions, though this approach lacks formal validation

Like all aspects of being human, there is diversity in our GLP-1 system, depending on our metabolic health profile (Huber et al, 2024)

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Combined with the GLP-1-mediated improvements in insulin sensitivity and the GIP-mediated changes in lipid metabolism, the triple agonist creates conditions under which the liver clears accumulated fat at rates never before observed in clinical settings

The clinical trial study is slated to run until November of 2027