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(2023), they describe a Dutch study which followed children taking melatonin for over 3 years found no significant long term negative effects on the children (including on puberty which was one of the concerns)

Dysbiosis of intestinal microbiota in early life aggravates high-fat diet induced dysmetabolism in adult mice

Formulated for optimal absorption, liposomal technology encapsulates Vitamin C in tiny fat-like spheres (liposomes), shielding it from acids and ensuring it reaches cells effectively

That is a reasonable conversation to have with your prescriber, especially when side effects, cost, or access are concerns

5775, pubmed.ncbi.nlm.nih.gov/1574445/, Morris, Gerwyn, et al