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They propose based on rodent and monkey studies that this kind of molecule, when administered at high enough doses, may result in weight loss comparable to the weight loss seen with drugs that include GLP-1 as a target, and without the tolerability issues like nausea and vomiting that often come with the approved treatments, according to a peer-reviewed draft paper published this week
Yes, GLP-1based medications have received FDA approval for weight loss treatment
The possibility of using GLP-1 receptor agonists more broadly offers hope for better managing these conditions, improving patient outcomes and enhancing quality of life
However, on GLP-1 therapy, appetite is already significantly reduced [4] many patients naturally eat well below their TDEE without counting calories
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