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Overall, these animal studies demonstrate the cognitive feed-forward hunger regulation mechanism that occurs in the hypothalamic region

Khamis T, Hegazy AA, El-Fatah SSA, Abdelfattah ER, Abdelfattah MMM, Fericean LM, Arisha AH (2023) Hesperidin mitigates cyclophosphamide-induced testicular dysfunction via altering the hypothalamic pituitary gonadal axis and testicular steroidogenesis, inflammation, and apoptosis in male rats

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In summary, multimodal therapy that integrates drug interventions with structured rehabilitation represents a paradigm shift in ICH management

Trends Pharmacol Sci 2006