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Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes

doi: 10.1016/S2468-1253(20)30331-9

These therapies improve glycemic control and aid in weight management, offering a less invasive alternative to injectable GLP-1 treatments while enhancing patient convenience and compliance

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Notably, in patients with SBS or after jejuno-ileal bypass surgery, delivery of an increased amount of undigested carbohydrates to the colon can result in excess d-lactate accumulation (185, 186)