Bioidentical hormone replacement for perimenopause and menopause
Gel pictures were captured using UV Lab (4.1.0) software
doi: 10.1073/pnas.82.23.7965 185 BarronBCYuN-TKuckJFRJ
Oral supplements are capsules, liposomal liquids, or powders taken at home
Abbreviations MS: Multiple sclerosis MOG: Myelin oligodendrocyte glycoprotein EAE: Experimental autoimmune encephalomyelitis CNS: Central nervous system BBB: Blood brain barrier LPS: Lipopolysaccharide CSF: Cerebro-spinal fluid GO: Gene ontology FFPE: Formalin-fixed paraffin-embedded PBMC: Peripheral blood mononuclear cells GSEA: Gene set enrichment analysis ADME: Absorption, distribution, metabolism, and excretion MRM: Multiple reaction monitoring ANOVA: Analysis of variance PLSDA: Partial least squares-discriminant analysis CV: Coefficient of variance References Abubakar M, Giri A, Goel F et al (2025) Diabetes, alzheimers disease risk factors, and the cafeteria diet: a comprehensive review
Gipr AP-KO and Gipr AP-GFP mice were next fed an HFD to induce DIO